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CHEM 537 Supramolecular Chemistry

The course introduces general principles of molecular recognition, complex formation and host design, with emphasis on thermodynamics of multi-site host-guest complexation and nature of supramolecular interactions. Structure, properties, and synthesis of major categories of cation-, anion-, and neutral molecule-binding hosts are discussed, and crystal structures of enzyme-inhibitor complexes are analyzed from the point of view of the basic concepts of host-guest chemistry. Credit units: 3 ECTS Credit units: 5.

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